Anti-metastatic effects of viral and non-viral mediated Nk4 delivery to tumours
نویسندگان
چکیده
منابع مشابه
Anti-metastatic effects of viral and non-viral mediated Nk4 delivery to tumours
The most common cause of death of cancer sufferers is through the occurrence of metastases. The metastatic behaviour of tumour cells is regulated by extracellular growth factors such as hepatocyte growth factor (HGF), a ligand for the c-Met receptor tyrosine kinase, and aberrant expression/activation of the c-Met receptor is closely associated with metastatic progression. Nk4 (also known as Int...
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Recent advances in molecular biology combined with the culmination of the Human Ge‐ nome Project [1] have provided a genetic understanding of cellular processes and disease pathogenesis; numerous genes involved in disease and cellular processes have been identi‐ fied as targets for therapeutic approaches. In addition, the development of high-throughput screening techniques (e.g., cDNA microarra...
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ژورنال
عنوان ژورنال: Genetic Vaccines and Therapy
سال: 2009
ISSN: 1479-0556
DOI: 10.1186/1479-0556-7-5